The MRCT Center Podcast

EP 1 - Trials Beyond Borders: CRO Perspective

This is the first episode in our new series, "Trials Beyond Borders: Building Representative Clinical Trials Worldwide."  This episode features a conversation with MRCT Center Program Director Willyanne DeCormier Plosky, consultant Katherine Wright, and Tinaya Gray, Global Head of Diversity in Clinical Trials at ICON, plc, about the CRO perspective, focusing on communication between sponsors, CROs, and sites in planning for diversity action plans in the context of global trials.

EP 2 - Trials Beyond Borders: Sponsor Perspective

In this episode, Racquel Bruton, Associate Director and Clinical Trials Diversity Portfolio Lead at Biogen, and Willyanne DeCormier Plosky, Program Director at the MRCT Center, discuss how sponsor companies are enhancing representation in clinical trials, particularly outside the US. Racquel highlights Biogen's longstanding commitment to reaching underrepresented populations and explores how the MRCT Center’s roadmap can help organizations develop effective diversity action plans.
Resources:
Representation in Research/Global Populationshttps://mrctcenter.org/representation-in-research/global_dei/
Global Representation Roadmaphttps://mrctcenter.org/resource/global-representation-roadmap/

Ep 3 - Advancing Pediatric Platform Trials

Episode Overview:In this special episode, recorded during the MRCT Center’s October 2024 conference, Advancing Pediatric Platform Trials: Streamlining Development, Maximizing Impact, we feature a keynote conversation with Dr. Danny Benjamin—renowned pediatrician, researcher, and champion of clinical trial innovation.
Dr. Benjamin discusses how platform trials can address persistent gaps in pediatric therapeutic development and why a coordinated, multi-stakeholder approach is critical to success. His insights, drawn from decades of leadership in this space, speak directly to the opportunities and operational challenges detailed in the MRCT Center’s post-conference report.
Key Discussion Topics:
Why traditional clinical trial models often fail pediatric populations
The case for multi-arm, multi-sponsor platform trials in rare and common childhood conditions
Governance and operational infrastructure to support long-term trial viability
Lessons learned from the Pediatric Trials Network and other collaborative efforts
The importance of global alignment, data sharing, and ethical considerations in trial design
Learn More:Explore the full Executive and Full Reports from the October convening:🔗 Advancing Pediatric Platform Trials: Streamlining Development, Maximizing Impact
About the Guest:Dr. Danny Benjamin is the Kiser-Arena Distinguished Professor of Pediatrics at Duke University and a national leader in pediatric drug development. He serves as Principal Investigator of the Pediatric Trials Network and has been instrumental in shaping evidence-based approaches to clinical research in children.
Subscribe & Share:If you value practical, ethical, and globally relevant conversations about clinical research, subscribe to the MRCT Center podcast. Share this episode with colleagues and visit mrctcenter.org to explore more.

EP 4 - Trials Beyond Borders: Clinical Trials in Latin America

Trials Beyond Borders: Clinical Trials in Latin America—Aligning Global Research with Local Realities
In this episode, Dr. Carla Saenz, Regional Advisor for Bioethics at the Pan American Health Organization (PAHO), joins Willyanne DeCormier Plosky, Program Director at the MRCT Center, for a compelling conversation on the clinical trial landscape in Latin America.
Together, they explore:
How population demographics, different hospital systems, and insurance models influence trial participation and representation
Ethical and regulatory pathways to increase inclusion in research
The role of international guidance, including the CIOMS guidelines, in shaping ethical trial conduct
Opportunities to design global trials that reflect and respect local contexts—without compromising scientific rigor
This discussion underscores the importance of equitable access and locally relevant research in an increasingly global clinical trial ecosystem.
For more about the MRCT Center’s work on Global Representation in Clinical Trials, click here or go to https://mrctcenter.org/representation-in-research/global_dei/.